Protein Modification Reagents
Worthington Biochemical Corporation COLLAGENASE TYPE 1 FLTRD 1GR
Collagenase, Type 1 (Code: CLS-1), which is filtered through a 0.22 micron membrane and lyophilized in vials.
![Medchemexpress LLC Propanoic acid, 3-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester | 1807521-07-8 | >95.0% | 406.39 g/mol | C19H22N2O8 | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000204285.png-250.jpg)
Medchemexpress LLC Propanoic acid, 3-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester | 1807521-07-8 | >95.0% | 406.39 g/mol | C19H22N2O8 | 500 MG
Ald-Ph-amido-PEG2-C2-NHS ester is a nonclaevable 2-unit PEG linker for antibody-agent-conjugation (ADC)
![Medchemexpress LLC Acetic acid, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]- | 172531-37-2 | 99.8% | 233.22 | 100 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000404593-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Acetic acid, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]- | 172531-37-2 | 99.8% | 233.22 | 100 MG
N3-PEG3-CH2COOH (PROTAC Linker 14) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent containing an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
Sigma Aldrich Fine Chemicals Biosciences Collagenase from Clostridium histolyticum | 9001-12-1 | MFCD00130830 | 500mg
Collagenase from Clostridium histolyticum | Purity: % | Mol Wt: 68-130 kDa | 9001-12-1 | MFCD00130830 | 500mg
Medchemexpress LLC DBCO-PEG2-acid | 2304558-25-4 | >=95.0% | C26H28N2O6 | 50 MG
DBCO-PEG2-acid is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It functions as a click chemistry reagent, featuring a DBCO group that enables strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing azide groups. PROTACs themselves are composed of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein, allowing PROTACs to exploit the intracellular ubiquitin-proteasome system for selective protein degradation.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Features a DBCO group for SPAAC
- Reacts with azide-containing molecules
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Creative Biomart Pancrelipase
The product, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands.
Medchemexpress LLC Methoxy-polyethylene glycol-distearoylphosphatidylethanolamine sodium salt | 95.0% | 3,000 Da (average) | 250 MG
m-PEG-DSPE sodium (MW 3000) is a methoxy-polyethylene glycol-conjugated distearoylphosphatidylethanolamine supplied as the sodium salt for research use. It is used as a PEG lipid in nanoparticle and micelle formulations to extend circulation time, improve colloidal stability, and reduce protein adsorption in colloidal drug-delivery systems.
- PEGylated phospholipid sodium salt for surface modification.
- Average molecular weight ~3,000 Da reflecting PEG chain length.
- Purity approximately 95.0% as specified by the manufacturer.
- Suitable for formulation of liposomes, lipid nanoparticles, and micelles.
- Improves circulation time and reduces opsonization.
- Supplied as a small-scale research package for laboratory use.
Medchemexpress LLC TCO-PEG2-amine | 2141981-87-3 | ≥97.0% | C15H28N2O4 | 50 MG
TCO-PEG2-amine is a PEG-based PROTAC linker. This compound is used in the synthesis of PROTACs.
- Purity of ≥97.0%
- Molecular formula C15H28N2O4
- Molecular weight 300.39
- Appears as a colorless to light yellow liquid
- Recommended storage at 4°C, protected from light
- Suitable for PROTAC synthesis
Sigma Aldrich Fine Chemicals Biosciences Pepsin Reagent Ready to Us
PEPSIN Pepsin Reagent Ready to Us
Sigma Aldrich Fine Chemicals Biosciences Collagenase Type Cls 100MG
This product is identical to Biochrom GmbH part numbers C2-22 and C2-28. Enzyme blending from collagenase clostripain with tryptic and proteolytic activities from Clostridium histolyticum. This preparation shows a high clostripain activity with the tryptic activity close to type I. Suitable for liver bone thyroid heart and salivary gland tissue. Specific activity is 125 to 250 Mandl units per milligram of powdered substance.
Gold Biotechnology Inc DTT (Dithiothreitol) (> 99% pure) Protease free 25 g
Dithiothreitol (DTT) is the common name of the more popular of the two Cleland’s Reagents (the other being Dithioerythritol or DTE). DTT is a powerful reducing agent that forms a stable six-membered ring with an internal disulfide bond which is resistant to oxidation. DTT is often used for the following: reducing the disulfide bridge of the cross-linker N,N′-bis(acryloyl) cystamine to break apart the matrix of a polyacrylamide gel, the reduction of disulfide bonds in proteins, the prevention of those bonds from forming between cysteine residues and lastly, DTT is often used to reduce thiolated DNA in order to minimize dimerization.